Free & Open API

ImmunoCheck

Instantly assess MHC-II epitopes, humanization, and developability of any antibody — no API key required.

MHC-II Epitope PredictionHumanization ScoringDevelopability Profiling

No API key required. Free for academic and commercial use.

Everything You Need to Assess Your Antibody

Five validated analyses, one API call.

MHC-II Epitope Prediction

Identify immunogenic peptides binding to common HLA-DR/DP/DQ alleles.

Humanization Scoring

Germline identity, T20 score, framework hallmark residue checks.

Developability Profiling

MW, pI, GRAVY, instability index, aggregation hotspots, sequence liabilities.

Fast & Lightweight

Sub-second response time. No ML inference, just rigorous biophysics.

No API Key Required

Open access for academic and commercial use. Rate-limited at 5 req/min.

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Playground

Try it now

Paste an antibody sequence and analyze in real-time.

Format:

Use it from your code

Drop-in REST API. No SDK, no auth.

import requests

response = requests.post(
    "https://api.jfinnova.es/api/v1/immunocheck",
    json={
        "sequence": "QVQLVESGGGLVQPGGSLRL...",
        "format": "VHH",
        "include_epitopes": True
    }
)

data = response.json()
print(f"Risk: {data['overall_risk']} ({data['risk_score']}/10)")
print(f"Humanization: {data['humanization']['humanization_grade']}")
print(f"Developability: {data['developability']['developability_grade']}")
POST api.jfinnova.es/api/v1/immunocheck5 requests/min (free)Full API docs

Start analyzing your nanobodies today

Free, no registration. Assess immunogenicity risk before committing to expensive wet-lab validation.

No API key neededAcademic & commercial useBuilt by JFInnova